Why do mosquitoes not bite when you sleep in air conditioning? Mosquitoes find bodies to bite when they detect a current of air containing the CO2 and odorants that mark a warm-blooded body. They fly into the current until they reach the source of the odors. If you are in an air-conditioned room 1) The air is circulating and the mosquitoes will have a hard time pinpointing your location. 2) The windows are probably closed so they won't be able to get into your home in the first place 3)The mosquitoes generally love warm and humid weather and when you have put your AC, its generally less warmer than the surrounding areas and hence mosquitoes stay away from your room.